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A combined feature set was generated by merging untargeted metabolite features and named metabolites into a single metabolite feature list

Cys151 residue is required to inhibit Keap1-mediated Nrf2 degradation, thus itaconate upregulates Nrf2 levels via Keap1 alkylation ( Figure 3 )

Additionally, the inclusion of inositol in some formulations can affect the solubility and stability of the mixture, thus it's important to follow specific guidelines provided for such cases

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