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The @NEJM just reported impressive weight loss with Orforglipron, the first oral small-molecule GLP-1 receptor agonist
M., & Hammond, B
This combination requires careful protocol design because both compounds affect metabolic pathways, and potential interactions have not been characterized in controlled clinical studies
Synergizes beautifully with B12 injections
Studies have shown that HO-1 may be involved in the development of diabetic complications like diabetic kidney, diabetic cardiovascular disease, and diabetic wound healing
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