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Chen JJ, Mollan SP (2025) Treatment and monitoring of idiopathic intracranial hypertension
In the main per-protocol analyses, participants were followed from the index date to first mutually exclusive incidence of SIS, discontinuation of study drug (defined as more than 60 days without drug supply), initiation of other study drug, or switch to other glucose-lowering drug (defined as filling a prescription for any glucose-lowering drug other than the baseline treatment or metformin and not refilling the assigned drug for 60 days), death, or end of follow-up
Andrology 13 , 20222034 (2025)
An enzyme called glutathione-S-transferase uses your glutathione stores to bind with the acetaldehyde and move it out of your system
A minor portion of the drug is metabolized in the liver by the cytochrome P450 enzymes (primarily CYP2E1) to the reactive and toxic APAP intermediate, N -acetyl-p-benzoquinone imine (NAPQI) (Patten et al
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