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12 This may be in part due to the observation that the aforementioned side effects tend to decrease over time with ongoing treatment, potentially due to tachyphylaxis/tolerance, 13,14 or that patients who experience more severe symptoms related to delayed gastric emptying may stop the medication early
The real benefits of GLP-1 agonists extend FAR beyond cosmetic weight loss
A recent review found people who quit these drugs regained an average 0.4 kg every month, and are estimated to regain all their lost pounds within 1.7 years
The medication stimulates the pancreas to release insulin when blood sugar is high to reduce blood sugar levels after meals
DPP-4 inhibitors have not been tested for such extended periods of time, and large-scale cardiovascular outcomes trials have not been designed to evaluate the effects of treatment with these drugs on microvascular risk
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