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Table 1 gives a summary of the clinical phase III studies with at least 52 weeks duration on the efficacy of DPP-4 inhibitors compared to sulfonylureas as add on therapy to metformin, respectively, in patients not reaching their glycaemic goals with a monotherapy of metformin

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In clinical studies of Huntingtons disease, treatment-emergent adverse events included somnolence and sedation, urticaria, rash and insomnia

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