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While more human data is needed, its mechanism aligns with many principles of functional and longevity medicine namely, supporting mitochondria, reducing inflammation, and improving insulin sensitivity
In SUSTAIN-6, retinopathy complications were higher (3.0% vs 1.8% with placebo), likely tied to fast blood-sugar improvement in people who already had retinopathy
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Hawkesford, Malcolm J
The women all lost substantial weight while on the drug
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