Since B12 is naturally found almost exclusively in animal products, those on strict plant-based diets often lack an adequate source of the vitamin
Guide for the Care and Use of Laboratory Animals , 8th ed, 220 (National Academies Press, 2011)
NNMT plays a key role in metabolic dysfunction, and its inhibition has been shown to reverse obesity-related changes in adipose tissue. Kraus et al., Cell Metabolism How 5-Amino-1MQ Works The primary mechanism behind 5-Amino-1MQ lies in its ability to inhibit nicotinamide N-methyltransferase (NNMT) an enzyme that is often overexpressed in fat cells, cancer cells, and aging tissues
It works by inhibiting the NNMT enzymea known contributor to fat storage and metabolic slowdown
Simpler, fewer variables, fewer potential issues