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In contrast, the subjects of clinical trials are complex patient populations, particularly elderly individuals with comorbid sarcopenia, obesity, or multiple metabolic diseases, whose muscle metabolic foundation is more fragile [63]

CSF remains a rich source of biomarkers, particularly in AD, where the core trio, A 142 , phosphorylated tau (p-tau), and total tau (t-tau), form the basis of the ATN framework

Next generation of weight management medications: implications for diabetes and CVD risk

Therefore, anti-inflammatory therapies targeting these pathways have emerged as key strategies for mitigating secondary brain injury

However, TNF- also helps regulate intestinal epithelial cell death and injury or repair