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Traversy, G
When adverse effects do occur following high-dose B12 administration, they are typically mild, transient, and often related to the route of administration rather than the vitamin itself
When stratified by administration route, the mean percentage changes were: Intramuscular (IM): 307% Oral: 285% Sublingual: 199% IM administration showed the highest average B12 increase, although oral and sublingual routes also yielded substantial improvements, supporting their use as effective and less invasive alternatives
Diet is the best way to prevent a vitamin B12 deficiency for someone with UC
