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Further researches, encompassing a larger, stratified, and including newly diagnosed patient population, are requisite to further elucidate these potential interactions

For some people, these side effects were too rough to continue treatment

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This effect is more pronounced with short-acting GLP-1 agents and tends to diminish over time with long-acting formulations

While the clinical relevance of these findings in a population largely free from kidney disease remains uncertain, the reductions in albuminuria, blood pressure, and the favourable safety profile support further investigation of retatrutides potential kidney-protective effects in high-risk populations