Retatrutide (research code LY3437943) is a single-molecule triple agonist that activates the GIP receptor, the GLP-1 receptor, and the glucagon receptor
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The Clinical Pharmacology of GLP-1 Receptor Agonists GLP-1 receptor agonists mimic the incretin hormone glucagon-like peptide-1, which the gut releases after eating
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Quality specifications Reference-grade Retatrutide is characterized at minimum by reverse-phase HPLC purity (99% by HPLC, ESI-MS verified), electrospray-ionization mass spectrometry confirming the expected monoisotopic mass, and quantitative amino-acid analysis where applicable