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A recurring theme across non-incretin metabolic peptides is that early development efforts were constrained by pleiotropy, cardiovascular effects, or incomplete receptor characterization rather than by lack of metabolic relevance
Asparagine deprivation enhances T cell antitumour response in patients via ros-mediated metabolic and signal adaptations
Sugase T, Akimoto T, Kubo T, Imai T, Otani-Takei N, Miki T, et al
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