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Different cellular and pathological disorders including calcium imbalance, altered mitochondrial dynamics, impaired biogenesis, oxidative stress, defective mitophagy, impaired mitochondrial trafficking, and dysfunctional respiratory chain lead to the development of mitochondrial dysfunction with subsequent progression of PD due to degeneration of DNs (Fig

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The 15 mg/kg dose was selected based on established efficacy and safety relative to known copper toxicity thresholds

Start only with medical guidance, and track what changes after you begin