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International Journal of Molecular Sciences 25(14)

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Mechanistically, efferocytosis can induce macrophage proliferation, a process reliant on apoptotic cell-derived nucleotides activating the mTORC2/Rictor pathway and efferocytosis-generated lactate stabilizing the Myc protein via GPR132 signaling, collectively expanding the pro-resolving macrophage pool and facilitating tissue injury resolution (86, 87)

For comprehensive information on potential issues, see the copper peptides side effects guide