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On metabolic stress, ASCT2 ( SLC1A5 ), LAT1 ( SLC7A5 ), CAT1 ( SLC7A1 ), GLYT1 ( SLC6A9 ), and xCT, the light chain subunit of system (SLC7A11), are elevated by ATF4 activation, which facilitates the uptake of glutamine, leucine, arginine, lysine, glycine, and cystine (Lopez et al., 2007
Role of cysteine S -conjugate -lyase in the metabolism of cisplatin
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