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7f, g), and, as previously seen for islets, found significantly reduced lysosomal localisation of exendin-4-stimulated GLP-1Rs in -arrestin 2 KD versus control cells
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Lp(a) levels are estimated to be 90% hereditary .[ref] (Thats really high when it comes to hereditary estimates!) High Lp(a) increases the risk of cardiovascular events: Across large cohorts, higher Lp(a) roughly doubles the risk of heart attack, aortic stenosis, or major cardiovascular events compared to low Lp(a)
Egecioglu et al., 2013c
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