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In cell-based and biochemical laboratory research, GHK-Cu has been investigated for its copper-binding behaviour and, in preclinical models, for associations with pathways relating to gene expression, extracellular matrix turnover and oxidative-stress responses

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Nitric oxide (NO) is a free radical gas molecule produced endogenously from L-arginine, oxygen, and NADPH by an enzyme nitric oxide synthase (NOS) [139]