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Beyond heat exposure - new methods to quantify and link personal heat exposure, stress, and strain in diverse populations and climates: the journal temperature toolbox

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The Ongoing Telmisartan Alone and in combination with Ramipril Global Endpoint trial (ONTARGET) was one of the earlier trials of dual RAAS blockade, randomizing 25,000 participants with vascular disease or diabetes to ramipril, telmisartan, or both

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This trend aligns with the rise of GLP-1 drugs

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Tumors with inherited or somatic deficiencies in HRR genes, such as BRCA1, BRCA2, PALB2, and RAD51, exhibit synthetic lethality to PARPis, including olaparib, rucaparib, niraparib, and talazoparib, which have shown durable efficacy in BRCA-mutant breast, ovarian, and prostate cancers

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