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L-carnitine emerged as one of the few dietary supplements showing significant efficacy in reducing fatigue in ME/CFS patients according to a systematic review, notwithstanding methodological limitations such as small sample size and potential selection bias [136]

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On the other hand, antioxidants can protect the cells from incident radiation through specialized pigments and control the levels of reactive species which otherwise might cause a cascade of reactions and lead to the generation of pathological oxidants [63]

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