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The primary mechanism of action involves binding to IGF-1 receptors on the surface of cells, activating intracellular signaling pathways such as the PI3K/Akt and MAPK pathways
Cogn Comput
MOTS-c A mitochondrial-derived peptide often discussed for supporting metabolic flexibility and cellular energy production
Cancer Res 64 : 236242 Girnita L, Girnita A, Brodin B, Xie Y, Nilsson G, Dricu A, Lundeberg J, Wejde J, Bartolazzi A, Wiman KG, Larsson O (2000) Increased expression of insulin-like growth factor I receptor in malignant cells expressing aberrant p53: functional impact
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