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Graves Disease : Causes hyperthyroidism, affecting the thyroid

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Huo Y, Li J, Qin X, et al

In short-term trials, particularly those involving HIV patients experiencing muscle wasting, the hormone has been administered in doses up to 0.1mg per kg of body weight for up to three months

Cortisol elevation is problematic because chronic cortisol excess promotes muscle breakdown, fat storage, immune suppression, and sleep disruption the opposite of what individuals seeking GH optimization want