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Eli Lilly reported its first Phase 3 readout (TRIUMPH-4) in December 2025, showing about 28.7% weight loss at 68 weeks, and a larger pivotal trial (TRIUMPH-1) in May 2026 showing about 28.3% weight loss at 80 weeks in 2,339 participants
This could theoretically affect DNA methylation, gene expression, and other processes dependent on methylation
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When paired with NAD+ injections, they create a boost that enhances cellular function, improves recovery, and elevates daytoday performance
Several other recent studies in both young and old individuals have shown significant benefits from additional protein but only when combined with exercise
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