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We compared the activity of wild-type BoNT/X and X(PC) on fusion proteins containing the targeted regions of either procaspase-1 (residues 304320) or VAMP1 (residues 2888), inserted between maltose-binding protein (MBP) and glutathione S -transferase (GST) proteins to facilitate bacterial expression and purification of these substrates
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The peptide particularly influences matrix metalloproteinases (MMPs) , enzymes that break down extracellular matrix components
Images were pseudocolored with the ratio of fluorescence excited at 407 nm and 482 nm
Cardiovascular exercise creates additional caloric deficit and improves insulin sensitivity
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