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Research published in the context of the SURPASS trial program demonstrated that tirzepatide produced dose-dependent HbA1c reductions of 1.24 to 2.58 percent across the studied dose range, and body weight reductions of 5.4 to 11.7 kilograms in patients with type 2 diabetes
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Many patients taking GLP-1 receptor agonists also use other medications that may affect fluid balance, including diuretics or SGLT2 inhibitors
One of the most impactful effects is sustainable weight loss, which can help restore ovulation and reduce many PCOS-related symptoms
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