In one long-term study, called the SURMOUNT-1 trial, people taking tirzepatide lost up to 25% of their starting weight over a period of 72 weeks
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Eric Topol (05:36): Well, also just to set the foundation here, which you alluded to, there had been so many attempts to come up with a drug that would work, not just of course in diabetes where there are many classes of drugs, but moreover, to treat the condition of obesity
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the primary abnormality is thought to be a specific defect of the renal secretory mechanism for potassium, which limits the kaliuretic response to, but not the sodium and chloride reabsorptive effect of, mineralocorticoid