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Key Research Characteristics: Selective NNMT inhibition, supporting studies into NAD metabolism and methylation pathways Investigated in the context of obesity, metabolic dysfunction, and lipid accumulation models Cell-permeable small molecule with favourable in vitro profile Studied for potential effects on adipocyte differentiation and energy expenditure Specifications: Form: Lyophilised powder For research purposes only
Brown et al., 2014
Beta-catenin accumulates, translocates to the nucleus, and binds to TCF/LEF transcription factors
Elevated -glucuronidase in the gut reactivates estrogen hormones that should be excreted from the body
