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Gradual incorporation of soluble fiber (oats, psyllium, legumes) and insoluble fiber (whole grains, vegetables, wheat bran) to achieve recommended daily intake (approximately 25g for women, 38g for men) can significantly improve stool consistency and frequency

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Labs are often rechecked at 36 months and then periodically

Most published trials track outcomes for 812 weeks, leaving a meaningful gap in our understanding of cumulative adverse events beyond the acute dosing window

Once participants reached their target dose and maintained it, GI symptoms decreased substantially