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Research in experimental colitis models shows BPC-157 treatment leads to enhanced mucosal healing and reduced inflammatory markers including NF-B activation, demonstrating translation of molecular anti-inflammatory mechanisms into tissue-level protection and repair enhancement

44 Due to these promising results, as well as its established cardiovascular safety, 42,45 investigational interest around this agent is intense, with multiple randomized trials exploring its effects on liver fibrosis and steatosis of diabetic and nondiabetic patients, when administered alone, in combination or in comparison with other agents, such as empagliflozin (on diabetics-NCT04639414), efinopegdutide (on diabetics and non-diabetics-NCT04944992), cilofexor and firsocostat (on diabetics and non-diabetics-NCT04971785)

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V.et al (2010)