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This allows the full dose to deposit in the tissue and prevents medication from leaking back through the needle track when you withdraw

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It also improves retention on a reversed-phase column, so standard chromatography suits it well

What sets it apart from Ipamorelin: Sermorelin was FDA-approved under the brand name Geref first as a diagnostic agent in 1990, then for GH deficiency in children in 1997 (Federal Register, PubMed)