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Post-ischemic glutamate surges activate NMDA receptors clustered in lipid rafts, causing lethal calcium influx and neuronal death, and interventions targeting raft cholesterol (e.g., statins) reduce NMDA receptor hyperactivation (Besshoh et al., 2005
References Pickart, L., and A
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The same mechanism that extends the replicative life of healthy cells also supports the proliferation of cancer cells, which are defined by their ability to bypass normal telomere-based growth limits
To better understand the reliability of the reviewed studies, we conducted a methodological quality assessment based on key design features, including randomization, blinding, use of control groups, and sample size
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