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Weight loss results depend on lifestyle habits, diet, physical activity, and metabolism
A prior episode of pancreatitis is not a formal contraindication, but the label advises against restarting after a confirmed episode
The clinical case for long-term obesity pharmacotherapy has been strengthened by SELECT trial cardiovascular outcome data, growing insurance coverage mandates, and the demonstrated durability of weight loss maintenance in patients who remain on GLP-1 therapy
The self-pay pricing through NovoCare at $499 per month for semaglutide, with some doses available at $149 to $199, represents the manufacturer direct-purchase option for patients who do not qualify for other programs
Behavioral maintenance also matters because appetite return can reactivate old patterns
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