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Estrogen influences where that fat sits and how readily it is released, which is why many women notice weight settling around the hips and thighs earlier in life, then migrating toward the midsection as hormone levels change
Primary action: IGF-1 receptor agonist at muscle satellite cells and myocytes
Source: #GLP1 #MentalHealth #MetabolicHealth #Longevity #HealthLongevitySecrets GLP-1s are changing obesity care but nutrition may be the silent side effect. As Jorge Urbina and colleagues highlight in a 2026 Clinical Obesity narrative review, GLP-1 receptor agonists (e.g., semaglutide, liraglutide, tirzepatide) can predispose some patients to micronutrient and nutritional deficienciesvia appetite suppression, delayed gastric emptying, and altered intake/absorption
Marc JeanGilles, DO, FACOG provides guidance on what patients typically experience during the first week after starting Ozempic (semaglutide)
The best peptides for tendon repair guide covers these applications in detail
