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Treating a patient population already diagnosed with a neurodevelopmental or neurodegenerative disorder presents greater challenges than what is presented in a laboratory, since these patients will present with varying levels of disease severity and/or progression with associated cellular damage and neuroinflammation
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Oxidative stress then accelerates the aggregation of -synuclein which subsequently binds and sequesters available GSH, creating a destructive feedback loop of protein misfolding and antioxidant loss ( 3.4 Multiple sclerosis Multiple sclerosis (MS) is a chronic autoimmune disease that affects the CNS
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