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In summary, these nanoparticle platforms achieve multi-targeted intervention in mitochondrial dysfunction through environmentally responsive drug release and targeted delivery mechanisms, from ROS scavenging, membrane potential stabilization, ETC repair, to activation of the NAD+-Sirt1 axis and mitochondrial regeneration pathways, providing a new precision treatment model for RIRI therapy
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2020 Apr;35(4):54456
"Influence of velocity on the response to intravenous injections"
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