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Comprehensive transcriptome and proteome analyses have provided global views of mRNA and protein abundance of metabolic enzymes in kidney regions and nephron segments 24,25,26,27 , which are generally consistent with results of previous targeted analyses of enzyme activity, protein abundance, or substrate utilization

There is real science suggesting biological activity, but the clinical evidence is weak and conflicting

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These systems maintain high steady-state concentrations of small-molecule antioxidants including reduced glutathione (GSH) and vitamin C (VitC)

PMCID: PMC11397063