For example, for patients who have hypercholesterolemia, only pravastatin but not atorvastatin, could reduce the atherogenic lipoprotein-associated phospholipase A2 (Ky et al., 2008), and lovastatin, but not pravastatin, causes higher mortality of cardiomyopathic hamsters (Mrz et al., 2000)
However, these florescent probes are susceptible to various drawbacks such as photo-bleaching and molecular leaching from the host, which may result in serious experimental artifacts 6,7,8,9
Each is presented here strictly as an area of laboratory study
10.1186/s12864-017-3642-5 142 SellamA.DongoA.GuillemetteT.HudhommeP.SimoneauP
In brief, cells were harvested by centrifuging at 500 g for 5 min, followed by washing with PBS