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For the dose of CB-839 10 M, on average, 89% (range 79.2-92.7%) of HG-3 cells and 75% (range, 63-85,8%) of MEC-1 cells remained viable after 72 hours of incubation ( Figure 3B )

Giblin JT, et al

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10.1523/jneurosci.18-20-08417.1998 79 McConnellS

GPX keeps the thiol-disulfide balance in check and also collaborates with peroxiredoxins and glutathione-S-transferases (GSTs) to maintain redox homeostasis