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This corresponds to an absolute rate of 1.04 cases per 1000 individuals in the tirzepatide group and 2.02 per 1000 in the control group, yielding an absolute risk reduction (ARR) of 0.98 per 1000 (NNT=1020)
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Semaglutide mainly helps regulate insulin and appetite, while berberine may help improve insulin sensitivity at the cellular level and manage cholesterol levels
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