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Application of single-cell and spatial omics in deciphering cellular hallmarks of cancer drug response and resistance

(2) M A Heffernan 1, A W Thorburn, B Fam, R Summers, et al (2001) Increase of fat oxidation and weight loss in obese mice caused by chronic treatment with human growth hormone or a modified C-terminal fragment International Journal of Obesity and Related Metabolic Disorders, 2001 Oct, Volume 25 (Issue 10), Pages 1442-9

If a breastfeeding infant experiences an adverse effect related to a maternally ingested drug, healthcare providers are encouraged to report the adverse effect to the FDA

The resulting single-stranded cDNAs were used as templates in PCR reactions using gene-specific primers to amplify TGR (forward 5-CTATTTCCGTAGACGTCTGT-3 and reverse 5-AATACAGTTTCCTTCCCGTT-3) or GAPDH (forward 5-GTTTTGGTCGTATCGGGAGA-3 and reverse 5-ATGCGTTAGAAACCACGGAC-3)

Examples include people with PCOS, Crohns disease, certain forms of depression or anxiety tied to metabolic signaling, and patients with persistent inflammation where weight loss isnt the primary goal