For example, in a new study, patients who first used a daily topical treatment gel containing 0.1% adapalene and 2.5% benzoyl peroxide for 2-4 weeks before undergoing 3 treatments with Sebacia, spaced 1-2 weeks apart, saw an improvement of 66% at 3 months, as compared to those who had Sebacia alone (in the clinical trials), and showed 49% improvement at 3 months
This stability is largely attributed to its unique sequence of amino acids, which allows it to withstand relatively harsh environments, including gastric acids in vivo
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Severity of Deficiency The level of B12 deficiency affects the dose needed
Interactions and Clinical Considerations Chloramphenicol may reduce the blood response to vitamin B12 therapy