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The effectiveness of semaglutide is twofold: it slows gastric emptying, promoting satiety, and regulates appetite and blood sugar levels due to prolonged bodily activity
Additionally, GLP-2 increases the barrier function of the gut epithelium and regulates gastric motility, gastric acid secretion, and intestinal hexose transport [66, 67]
These higher doses are typically reserved for patients who have plateaued at lower doses despite good dietary and exercise habits
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