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However, the ChaC family is less studied in the myocardium [37]
Lancet 397(10278):971984 Garvey WT, Frias JP, Jastreboff AM et al (2023) Tirzepatide once weekly for the treatment of obesity in people with type 2 diabetes (SURMOUNT-2): a double-blind, randomised, multicentre, placebo-controlled, phase 3 trial
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From a mechanistic standpoint, these observations are mediated by GLP-1R in monocytes/macrophages and glomerular endothelial cells (Ye et al., 2019)
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(73) had two types of intervention (L-carnitine supplementation + aerobic training and L-carnitine supplementation) so we considered two arms for this study
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