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These include: Dulaglutide (Trulicity) : Once-weekly injection with a single-dose pen featuring an automatic injection mechanism Semaglutide (Ozempic) : Once-weekly administration with dose escalation from 0.25 mg to maintenance doses of 0.5 mg, 1 mg, or 2 mg Exenatide extended-release (Bydureon BCise) : Once-weekly microsphere suspension requiring resuspension before injection Liraglutide (Victoza) : Once-daily injection available in a multi-dose pen For weight management, semaglutide 2.4 mg (Wegovy) and liraglutide 3.0 mg (Saxenda) are specifically FDA-approved
doi: 10.1038/s41422-020-00441-1
8 weeks: ~23 vials 12 weeks: ~34 vials 16 weeks: ~45 vials Insulin Syringes (U-100, 1 mL) Per injection: 1 syringe 8 weeks (once daily): ~56 syringes 16 weeks (once daily): ~112 syringes Bacteriostatic Water (10 mL bottles) Use ~3.0 mL per 80 mg vial for reconstitution
Gallbladder disease : GLP-1 receptor agonists may increase the risk of gallstones (cholelithiasis) and gallbladder inflammation (cholecystitis)
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