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This distinction alone fundamentally changes the treatment calculus, because chronic conditions typically require chronic treatment, and obesity is a chronic condition
Figure 4 Myocardial hypertrophy and fibrosis TMAO significantly increased the mRNA and protein levels of the hypertrophic markers atrial natriuretic peptide (ANP) and -myosin heavy chain (-MHC), causing myocardial hypertrophy and fibrosis (94)
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Given the association of GSSG with the oxidative protein folding environment in the ER, we examined whether etomoxir could make the ER more oxidizing to proteins in the lumen
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