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Synthesis and pharmacological characterization of novel peripheral cannabinoid-1 receptor blockers based on a tricyclic scaffold

Indications and Efficacy: Obesity Treatment: In the Phase II clinical trial, patients in the highest dose group (12 mg) lost an average of 24.2% weight after 48 weeks, and some patients lost more than 30%

They are also beneficial for those with type 2 diabetes, as they address both blood sugar levels and weight concerns

Following the dosing instructions consistently is essential for maintaining steady blood sugar levels