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While these side effects can be mild, they can be very bothersome to some people
Szoka F, Papahadjopoulos D
Critically, there is a shortage of long-term rodent studies examining chronic exposure, reproductive toxicity, and tumor promotion
Genetic susceptibility: Variants in immune-regulation genes (e.g., HLA, NLRP1, PTPN22) and melanocyte function genes (TYR, KITLG) raise risk
10.1016/j.mrrev.2003.06.016
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