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Studies in rats [61] also suggested that both VPA and its unsaturated metabolites inhibit -oxidation through different mechanisms, such as sequestration of CoA-SH and direct inhibition of specific enzymes in the -oxidation sequence by CoA esters, particularly 4-en-VPA-CoA
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In this article, the effects of berberine on a variety of animal models were reviewed, mainly focusing on depression, anxiety, and the memory-related symptoms of Alzheimers disease
1 Introduction Ulcerative colitis (UC) is a chronic, relapsing form of inflammatory bowel disease (IBD) characterized by immune system dysfunction and pathological overactivation of mucosal immune responses, leading to persistent inflammation and subsequent colonic mucosal injury (Raine et al., 2022)
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