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Maridebart Cafraglutide (MariTide) is a unique medicine that acts as a GLP-1 receptor agonist and a GIP receptor antagonist
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Separation was conducted at a constant temperature of 30 C using a mobile phase of 5% (v/v) acetonitrile, 0.05% (v/v) trifluoroacetic acid, and 0.1 M sodium perchlorate at a flow rate of 0.5 mL/min
Baseline WOMAC pain score: approximately 6 out of 20 Reduction in active treatment arms: approximately 4.5 points , representing a ~76% decrease from baseline Complete freedom from knee pain at week 68: reported by roughly 1 in 8 patients (12.5%) receiving retatrutide, compared to just 4.2% in the placebo group A 76% reduction in pain scores is extraordinary approaching the range typically seen after total knee replacement surgery
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