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Results We found that ALCAR reduces cell proliferation, induces apoptosis, hinders the production of pro inflammatory cytokines (TNF- and IFN-) and of chemokines CCL2, CXCL12 and receptor CXCR4 involved in the chemotactic axis and impairs the adhesion, migration and invasion capabilities of PCa and BPH cells in vitro

The 500 Da rule, widely cited in dermatology literature (Bos and Meinardi, 2000, Contact Dermatitis), holds that molecules above 500 Da penetrate stratum corneum poorly

Symptoms are information, not inconveniences to ignore

Contraindications include active joint infection, blood clotting disorders, and certain autoimmune conditions

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