Patients with severe gastrointestinal disease, including gastroparesis, may not tolerate the medication well
IGF-1 DES: More pronounced peaks in lipolytic activity with more variable trough levels between doses
Prenatal CTB exposure led to fetal resorptions, fetal mortality, growth retardation, oxidative stress, and external developmental anomalies such as hematoma, phocomelia, oligodactyly, and impaired ossification in fetal axial and appendicular skeletal bones
Concentrations naturally decline with age (from about 200 ng/mL at age 20 to 80 ng/mL by age 60), which is part of why supplementation makes sense
Once LLY launches Donanemab , the market is expected to be evenly split between LLY and Biogens Leqembi